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Rubber chemicals

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Allergy among Danish eczema patients to rubber chemicals

Rubber chemicals can cause allergies.

 

The chemicals have different chemistry, and in the diagnosis of rubber chemical allergy both individual substances like mercaptobenzothiazole (MBT) and mixtures of substances such as mercapto mix and thiuram mix are used.

 

In black rubber other additives are used. These additives may also cause allergies. The substance N-isopropyl-N-phenyl-p-phenylenediamine (IPPD) is used either alone or mixed with other similar substances (black rubber mix) to detect this type of allergy.

 

Click on the graph to enlarge: 

 

See also figures in the tables below.

 

Mercaptobenzothiazol (MBT)

  Women Men Both sexes
2009  0,4 pct.  0,7 pct. 0,5 pct.
2008  0,8 pct. 1,0 pct. 0,9 pct.
2007  0,2 pct.  0,6 pct. 0,3 pct.
2006  0,7 pct.  0,8 pct. 0,7 pct.
2005  0,6 pct.  0,4 pct. 0,5 pct.
2004  0,4 pct.  0,3 pct. 0,4 pct.
2003  0,2 pct.  0,4 pct. 0,3 pct.

 

Mercapto mix

  Women Men Both sexes
2009  0,4 pct. 0,5 pct.  0,4 pct.
2008  0,8 pct. 1,2 pct.  0,9 pct.
2007  0,4 pct. 0,4 pct.  0,4 pct.
2006  0,9 pct. 0,8 pct.  0,9 pct.
2005  0,6 pct. 0,3 pct.  0,5 pct.
2004  0,2 pct. 0,4 pct.  0,2 pct.
2003  0,0 pct. 0,6 pct.  0,3 pct.

  

Thiuram mix

  Women Men Both sexes
2009  2,2 pct.  1,9 pct. 2,1 pct.
2008 1,9 pct.  1,8 pct.  1,9 pct.
2007  2,2 pct.  1,0 pct. 1,8 pct.
2006 2,1 pct.  1,3 pct.  1,8 pct.
2005 1,8 pct.  1,0 pct. 1,5 pct.
2004 2,1 pct. 1,5 pct. 1,9 pct.
2003  2,0 pct.  1,1 pct.  1,7 pct.

 

N-isopropyl-N-phenyl-p-phenylenediamine (IPPD)

  Women Men Both sexes
2009  0,5 pct. 0,4 pct.  0,5 pct.
2008  0,4 pct.  0,6 pct. 0,4 pct.
2007  0,5 pct. 0,9 pct. 0,7 pct.
2006  0,6 pct. 0,4 pct. 0,5 pct.
2005  0,6 pct. 0,7 pct. 0,6 pct.
2004  0,5 pct. 1,1 pct. 0,7 pct.
2003  0,5 pct.  0,1 pct.  0,4 pct.

 

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    National Allergi Research Centre    Gentofte Hospital    Niels Andersens Vej 65    DK 2900 Hellerup    +45 3977 7300     info@videncenterforallergi.dk    Contact web editor    Last updated 13-01-2011